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This gene is really a member of your SUMO gene relatives. This family of genes encode tiny ubiquitin-associated modifiers that are attached to proteins and control the goal proteins' subcellular localization, stability, or action. The protein explained In this particular report is found during the cytoplasm and particularly modifies IKBA, leading to unfavorable regulation of NF-kappa-B-dependent transcription of your IL12B gene.
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